E-Scan 625
Overview
The E-Scan 625 is an offline lab instrument that utilizes HVLD leak detection technology to inspect individual samples for container closure integrity. HVLD is completely non-destructive to the container, is a non-contact, non-invasive test with no sample preparation required. HVLD can be used on a wide range of liquid based products, including products with suspensions, emulsions and protein. Package/container material must be non-conductive (glass, plastic, poly laminates).
The HVLD test method ensures product seal integrity by scanning the product to detect small pinholes, micro cracks and seal imperfections. HVLD has proven to be a highly sensitive leak test method for various types of pharmaceutical packaging (pre-filled syringes, liquid filled vials, blow-fill-seal containers, liquid filled pouches).
The E-Scan 625 features a fast test cycle and is easy to operate. Additional benefits include quick changeover and easy test parameter changes to accommodate a wide range of products and applications. The HVLD method can be easily migrated from the laboratory offline to 100% inline testing applications at high production speeds.
Benefits
- Non-destructive, non-invasive, no sample preparation
- Defect detection down to 1 micron
- High level of repeatability and accuracy
- Cost effective with rapid return on investment
- Zero waste
- Simplifies the inspection and validation process
- Offline and 100% online inspection at high production speeds
Technology
The HVLD testing process consists of a set of electrode probes which scans a sealed container made of a non-conductive material. Materials can be glass, plastic or poly laminates. Container or package must contain liquid (minimum approx. 30%). If a pinhole, crack or other defect is present, there is a differential of the current flow (voltage) indicating a breach of the container closure. Approximate defect location can be determined when using the off line lab system. The actual test fixture can be designed for rigid containers (syringes, vials, ampoules, bottles) as well as for pouches and flexible packaging. The positioning and type of electrodes are determined by the package specifications and package orientation during the actual HVLD scanning process.
Inspection Criteria
- Detection of pinholes, cracks, and defective seals
- Measures and verifies container closure system integrity
E-Scan, a PTI and Nikka Technology